4-phytase
| 4-phytase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.26 | ||||||||
| CAS no. | 9001-89-2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme 4-phytase (EC 3.1.3.26) catalyzes the following reaction:
The enzyme characterised from wheat bran hydrolyses phytic acid (myo-inositol hexakisphosphate) to 1D-myo-inositol 1,2,3,5,6-pentakisphosphate and orthophosphate (Pi).[1][2] Addition of this enzyme to the diet of broiler chickens has been shown to prevent loss of nutrients in their excretions.[3][4]
The enzymes is a hydrolase, specifically one acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-hexakisphosphate 4-phosphohydrolase. Other names in common use include 6-phytase (name based on 1L-numbering system and not 1D-numbering) and phytate 6-phosphatase.[5]
See also
[edit]- 3-phytase (1-phytase)
- 5-phytase
- Protein tyrosine phosphatase
References
[edit]- ↑ Lim, P.E.; Tate, M.E. (1973). "The phytases. II. Properties of phytase fractions F1 and F2 from wheat bran and the myo-inositol phosphates produced by fraction F2". Biochimica et Biophysica Acta (BBA) - Enzymology. 302 (2): 316–328. doi:10.1016/0005-2744(73)90160-5. PMID 4349266.
- ↑ Mullaney EJ, Ullah AH (December 2003). "The term phytase comprises several different classes of enzymes". Biochemical and Biophysical Research Communications. 312 (1): 179–84. Bibcode:2003BBRC..312..179M. doi:10.1016/j.bbrc.2003.09.176. PMID 14630039.
- ↑ Cowieson, A.J.; Acamovic, T.; Bedford, M.R. (2004). "The effects of phytase and phytic acid on the loss of endogenous amino acids and minerals from broiler chickens". British Poultry Science. 45 (1): 101–108. doi:10.1080/00071660410001668923. PMID 15115207.
- ↑ Nezhad, Nima Ghahremani; Rahman, Raja Noor Zaliha Raja Abd; Normi, Yahaya M.; Oslan, Siti Nurbaya; Shariff, Fairolniza Mohd; Leow, Thean Chor (2023). "Isolation, screening and molecular characterization of phytase-producing microorganisms to discover the novel phytase". Biologia. 78 (9): 2527–2537. doi:10.1007/s11756-023-01391-w.
- ↑ Enzyme 3.1.3.26 at KEGG Pathway Database.
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